Characteristics of Bacilliq® /SporebioticTM


  • Bacillus subtilis HU58® maintains itself under colonic conditions and produces a 38% increase in Short Chain Fatty Acids (SCFA), mainly Butyrate which is important for a healthy immune system and intestinal epithelium.
  • Resporulation of B. subtilis HU58® plays a major role in the development of GALT - Gut Associated Lymphoid Tissue which is important for both adaptive and innate immunity.
  • Various studies have demonstrated the safety, bile and acid tolerance, mucin binding, and immune stimulation ability of Bacillus subtilis strains and its clinical efficacy in various gastrointestinal disorders.
  • Leads to a beneficial modulation of the intestinal environment both in terms of microbial community composition & activity. Thus it increases beneficial flora including Lactobacilli, Bifidobacteria, Bacteroides etc. and decreases pathogens such as E.coli, Salmonella spp etc.

Composition and dose of bottle/vial/capsule formulations


Benefits of Bacilliq® /SporebioticTM


Proven benefits in maintaining healthy immune system

  • Short Chain Fatty Acids (SCFA) mainly butyrate, has demonstrated beneficial effects on the development of a healthy immune system and gut health.
  • An open labelled trial conducted in healthy subjects showed that probiotic Bacillus subtilis HU58® at a dose of 2 billion CFU once a day for 8 weeks was well tolerated and has potential role in improving immune system of healthy subjects.1

Proven to resolve diarrhea

  • An open-labelled placebo-controlled trial conducted in a group of 60 patients with Antibiotic Associated Diarrhoea (AAD) proved the efficacy of probiotic Bacillus subtilis HU58®(dose of 2 billion CFU/Cap once a day for 7 days) in significantly reducing the incidence of AAD and was found to be safe and well tolerated by patients.2
References

1. Dound YA, Jadhav SS, Devale M et al. The effect of Probiotic Bacillus subtilis HU58 on Immune function in Healthy Human. The Indian Practitioner 2017; 70 (09): 15-20.
2. Mehta DS, de Souza A, Jadhav SS, et al. A Study of Probiotic Bacillus subtilis HU58 for the Management of Antibiotic-Associated Diarrhoea in Adults. The Indian Practitioner.2020;73 (4):22-28.